According to a study published in Annals of the American Thoracic Society, serum periostin is useful for detecting chronic rhinosinusitis with nasal polyps in asthmatic patients.

Japanese researchers compared 65 patients with stable asthma and found that asthmatics with chronic rhinosinusitis had higher serum periostin levels than those without upper airway disease.

Furthermore, asthmatics with chronic rhinosinusitis and nasal polyps had higher serum periostin levels than asthmatics without nasal polyps.

Serum periostin was the only biomarker that detected the presence of nasal polyps when comparing patients with comorbid chronic rhinosinusitis and nasal polyps to those without.

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