December 2006
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| Features |
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| MANAGING DISEASE |
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Attacking Cystic Fibrosis on Many Fronts |
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by John D. Zoidis, MD |
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Cystic fibrosis can be a devastating, even fatal, disease; but proper diagnosis and new treatments, coupled with breakthroughs in gene replacement therapy, offer improved outcomes. |
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α1-Antitrypsin Deficiency and Early-onset COPD |
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by Phyllis C. Braun, PhD |
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There is no cure for AAT deficiency, but behavioral and lifestyle modifications, coupled with drug therapy and AAT replacement therapy, and the promise of gene replacement therapy, offer hope. |
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Acid Aspiration: Inflammation and Resolution |
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by Frantz Hastrup, MD, and Bruce D. Levy, MD |
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Aspiration of oropharyngeal or gastric contents into the lower respiratory tract can lead to multiple respiratory diseases such as asthma, chemical pneumonia, and ARDS. Several compounds are currently being tested for their protective actions against inflammation that leads to lung injury. |
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