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U.S. FDA, CDC say Merck's Gardasil shot remains safe Jul 22, 2008
WASHINGTON (Reuters) - A review of health problems reported after women and girls received Merck & Co's Gardasil vaccine shows it remains safe and effective for protecting against a virus that causes cervical cancer, U.S. officials said on Tuesday.

Omeprazole boosts saquinavir exposure in HIV patients Jul 22, 2008
NEW YORK (Reuters Health) - In HIV patients taking saquinavir/ritonavir, use of omeprazole leads to a significant - and apparently well tolerated - increase in saquinavir plasma exposure.

Multi-drug resistance emerging in pneumococcal mastoiditis Jul 22, 2008
NEW YORK (Reuters Health) - The Streptococcus pneumoniae serotype that most often causes mastoiditis in children is becoming increasingly drug-resistant.

Inhaled mannitol improves lung function in cystic fibrosis patients Jul 22, 2008
NEW YORK (Reuters Health) - Treatment with inhaled mannitol leads to significantly improved lung function in patients with cystic fibrosis (CF), according to a report by Australian researchers in the June issue of Chest.

U.S. regulators reviewing latest Vytorin heart data Jul 22, 2008
WASHINGTON (Reuters) - U.S. drug regulators said on Monday they are reviewing the latest data that found Schering-Plough Corp and Merck & Co Inc's drug Vytorin failed to improve heart outcomes in a widely-watched clinical study.

GORE-TEX implants seen as safe alternative to graft for rhinoplasty Jul 22, 2008
NEW YORK (Reuters Health) - GORE-TEX (expanded polytetrafluoroethylene) implants are a safe and inexpensive alternative to autografts for use in rhinoplasty, according to the results of a 17-year retrospective review.

Gastroesophageal Reflux Disease Found to Add to Development of Asthma Jul 22, 2008
Findings shed light on the well-known relationship between the two conditions.

Obstructive sleep apnea may trigger nocturnal MI Jul 21, 2008
NEW YORK (Reuters Health) - The hemodynamic and neurohormonal changes wrought by obstructive sleep apnea (OSA) may increase the risk of MI during the night, new research suggests.

Gene expression profiles with clinical data prognostic for early stage lung cancer Jul 21, 2008
NEW YORK (Reuters Health) - Gene expression signatures predict survival in patients with early stage lung cancer, particularly when combined with clinical data, scientists report in the July 20 online issue of Nature Medicine. The researchers' comparison of several models showed that gene cluster expression analysis performed best.

Gene Panels Reveal Inforrmation on Lung Cancer Survival Jul 21, 2008
A collaborative study finds that gene panels identify which patients will have the worst survival rates.

Female gender and smoke exposure predict asthma response to montelukast Jul 18, 2008
NEW YORK (Reuters Health) - In children with asthma treated with inhaled corticosteroids and requiring rescue medication, responsiveness to the leukotriene blocker montelukast is increased in those exposed to tobacco smoke and tends to be greater in girls than in boys, according to investigators at the National Jewish Medical and Research Center.

Furosemide inhalation can alleviate dyspnea in COPD Jul 18, 2008
NEW YORK (Reuters Health) - Inhalation of furosemide relieves exertional dyspnea in some patients with chronic obstructive pulmonary disease (COPD), according to a report by researcher in Canada.

Zoledronic acid reduces fracture risk in cancer patients with bone metastases Jul 18, 2008
NEW YORK (Reuters Health) - The bisphosphonate zoledronic acid normalizes or maintains N-telopeptide of type 1 collagen (NTx) levels in cancer patients with bone metastases, a multicenter team reports in the July 1 issue of Cancer.

US Healthcare System Scores only 65 out of 100 Points Jul 18, 2008
New report shows US healthcare system is inefficient and failing to keep up with other countries.

Sleep disordered breathing common in patients with pulmonary hypertension Jul 17, 2008
NEW YORK (Reuters Health) - Cheyne-Stokes respiration and central sleep apnea are common in patients with pulmonary hypertension, and obstructive sleep apnea also occurs, according to findings published in the June issue of Chest.

Astellas wins Japan approval for once-daily formulation of tacrolimus Jul 17, 2008
TOKYO (Reuters) - Astellas Pharma Inc said on Thursday it had won approval to sell a new version of its key transplant drug in Japan, the second major region where it has gained approval although it is facing delays in the United States.

Limited benefit seen with docetaxel and rapid androgen cycling for prostate cancer Jul 17, 2008
NEW YORK (Reuters Health) - Because of a high incidence of neutropenia and little sustained response, docetaxel with rapid androgen cycling is not recommended for use in patients with progressive noncastrate prostate cancer, researchers report.

Clarithromycin, ciprofloxacin similar as add-ons for mycobacterial lung infections Jul 17, 2008
NEW YORK (Reuters Health) - Clarithromycin or ciprofloxacin as adjuncts to rifampicin and ethambutol produce similar outcomes in patients with opportunistic mycobacterial pulmonary infections, according to results from the largest randomized trial on this subject.

Palivizumab may prevent RSV infections in infants with cystic fibrosis Jul 17, 2008
NEW YORK (Reuters Health) - Data from the prospective Palivizumab Outcomes Registry indicate that prophylactic treatment with the monoclonal antibody prevents respiratory syncytial virus (RSV) lower respiratory tract infection among infants with cystic fibrosis.

J&J antibiotic safe, effective, U.S. panel says Jul 17, 2008
ROCKVILLE, Md. (Reuters) - Johnson & Johnson's antibiotic Doribax appears safe and effective for treating patients with pneumonia acquired in a hospital, a U.S. Food and Drug Administration advisory panel said on Wednesday.

Regular salmeterol use for asthma ups risk of serious adverse events Jul 17, 2008
NEW YORK (Reuters Health) - Patients with chronic asthma who use the long-acting beta-2 agonist salmeterol on a daily basis are at increased risk for serious adverse events, researchers conclude in the latest issue of The Cochrane Library.

Advisory Committee Votes in Favor of DORIBAX to Treat Pneumonia Jul 17, 2008
The use of DORIBAX for the treatment of hospital-acquired pneumonia is under regulatory review and has received positive opinion from an FDA advisory committee.

Eradicating nasal S. aureus does not improve allergic rhinitis Jul 16, 2008
NEW YORK (Reuters Health) - Topical nasal mupirocin is an effective means of eradicating Staphylococcus aureus nasal colonization in patients with perennial allergic rhinitis, according to Israeli researchers. However, the approach does not lead to clinical improvement.

Cyclophosphamide-based therapy slows progression of systemic sclerosis lung disease Jul 16, 2008
NEW YORK (Reuters Health) - Intravenous cyclophosphamide followed by oral maintenance immunosuppression with azathioprine improves or stabilizes lung function in systemic sclerosis (SSc) patients with worsening interstitial lung disease (ILD), according to a report in the June issue of The Journal of Rheumatology.

U.S. panel says J&J antibiotic effective Jul 16, 2008
ROCKVILLE, Md. (Reuters) - Johnson & Johnson's antibiotic Doribax appears effective for treating patients with pneumonia acquired during a hospital stay, a U.S. advisory panel said in a 7-6 vote on Wednesday.

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