Certain pulmonary outcome measures such as forced expiratory volumes before and after bronchodilation differed by gender during puberty, according to study results.

Researchers conducted longitudinal research on the Childhood Origins of Asthma (COAST) birth cohort study to identify any sex-associated relationships between lung physiology and asthma.

Girls, aged 5 to 11 years, had higher prebronchodilator FEV0.5/forced vital capacity (FVC) than did boys (mean difference, 0.017; 95% CI, 0-0.034). Data from postbronchodilator testing, however, showed that boys experienced a bigger reduction in FEV0.5/FVC than did girls of similar age (mean difference, 0.032; 95% CI, 0.014-0.049).