According to the FDA’s Vaccine Adverse Event Reporting System (VAERS) some patients have experienced allergic reactions after receiving egg-free recombinant influenza vaccine.

“The results of this limited analysis suggest that allergic reactions following influenza vaccination are not necessarily related to egg proteins,” Emily Jane Woo, MD, MPH, of the FDA’s Center for Biologics Evaluation and Research, wrote in Clinical Infectious Diseases.

“Vaccine providers and other health care professionals, as well as consumers, should be aware that allergic reactions — sometimes requiring emergency medical intervention — have occurred following routine immunization with [recombinant hemagglutinin influenza vaccine (RIV3)].”