A study in mice reveals that vapors from e-cigarettes can trigger substantial inflammation in the lung.

In lab mice, exposure to e-cigarette vapors for two weeks produced markers of blood nicotine comparable to those seen in people who smoke cigarettes and e-cigarettes. E-cigarette vapors also “produced mild effects on the lungs, including inflammation and protein damage,” notes Thomas Sussan of the Johns Hopkins Bloomberg School of Public Health, lead author of the study, published February 4 in PLOS ONE.